![]() ![]() The number and locations of substitutions in the spike protein.Transmission and replacement of the Delta variant in South Africa.Detection of cases attributed to Omicron in multiple countries, including among those without travel history.This classification was based on the following: government SARS-CoV-2 Interagency Group (SIG) classified Omicron as a Variant of Concern (VOC). SARS-CoV-2 genetic lineages in the United States are routinely monitored through epidemiological investigations, virus genetic sequence-based surveillance, and laboratory studies.Genetic lineages of SARS-CoV-2 have been emerging and circulating around the world since the beginning of the COVID-19 pandemic.
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